[4:56] Surely those who disbelieve in Our signs - We shall expose them to a Fire; as often as their skins are consumed, We shall replace them with other skins, that they may taste the chastisement. Surely God is ever Mighty, Wise.
The allusion from it is to those who deny the signs of the friends. He causes them to abide in a state of insignificance and causes them to remain the alienation of denial. Whenever something appears to their hearts from this story, their rejection leads them to abandon faith in it and to feel contempt for its people as a way of seeking distance, so they are punished over and over again.